Yeast infection species are frequently part of the human body's normal oral and intestinal flora. Treatment with antibiotics can lead to eliminating the yeast's natural competitors for resources, and increase the severity of the condition.
In clinical settings, yeast infection is commonly treated with antimycotics—the antifungal drugs commonly used to treat yeast infection are topical clotrimazole, topical nystatin, fluconazole, and topical ketoconazole. For example, a one-time dose of fluconazole (as Diflucan 150-mg tablet taken orally) has been reported as being 90% effective in treating a vaginal yeast infection. This dose is only effective for vaginal yeast infections, and other types of yeast infections may require different treatments. Local treatment may include vaginal suppositories or medicated douches. Gentian violet can be used for breastfeeding thrush, but when used in large quantities it can cause mouth and throat ulcerations in nursing babies, and has been linked to mouth cancer in humans and to cancer in the digestive tract of other animals.
Treating yeast infection solely with medication may not give desired results, and other underlying conditions may be the cause. Oral yeast infection can be the sign of a more serious condition, such as HIV infection or other immunodeficiency diseases. Maintaining vulvovaginal health can help prevent vaginal yeast infection.
C. albicans can develop resistance to antimycotic drugs, such as fluconazole, one of the drugs that is often used to treat candidiasis. Recurring infections may be treatable with other anti-fungal drugs, but resistance to these alternative agents may also develop.
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